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Table 2 Main virulence genotypes of clinical isolates in Shenzhen

From: Molecular epidemiology of Bordetella pertussis and analysis of vaccine antigen genes from clinical isolates from Shenzhen, China

Genotype

Strain number

Proportion

prn1/ptxA1/ptxP1/ptxC1/fim3-1/fim2-1

BG03,04,07,13,15,17,24,29,30,31,32,33,34,35,37, 45,46,47

18 (36%)

prn2/ptxA1/ptxP3/ptxC2/fim3-1/fim2-1

BG01,02,06,08,09,10,11,12,14,16,18,19,20,21,22, 23,25,26,27,28,36,38,39,40,41,42,43,44,48,49,50

31 (62%)

prn3/ptxA1/ptxP1/ptxC1/fim3-1/fim2-1

BG05

1 (2%)

prn1/ptxA2/ptxP1/ptxC1/fim3-1/fim2-1

CSa, TohamaIb

0 (0%)

  1. aCS strain is a Chinese strain isolated in Beijing and used for production of pertussis vaccine
  2. bTohama I strain is a strain isolated in Japan in the 1950s and widely used for production of pertussis vaccine.c These genes encode: pertactin (prn); pertussis toxin subunits S1 (ptxA) and S3 (ptxC); pertussis toxin promoter region (ptxP); fimbrial antigen 2 (fim2) and 3 (fim3)
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Annals of Clinical Microbiology and Antimicrobials

ISSN: 1476-0711

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