Fig. 8
Biofilm-formation inhibitory activity of BiF2_5K7K on S. epidermidis biofilm. A Biofilm cell viability after treatment with 0.98–250 µg/mL of BiF2_5K7K. B Confocal imaging of S. epidermidis biofilm treated with BiF2_5K7K at MBIC50. C The fluorescence intensity ratio of Alexa Flour® 488 stained biofilms. D and E The relative gene expression of S. epidermidis polysaccharide production and quorum-sensing genes, respectively. The data presented represent the mean ± SD of at least three independent experiments. Statistical significance is denoted by *p-value < 0.05, **p-value < 0.01, ***p-value < 0.001, and ****p-value < 0.0001, indicating the presence of significant differences in the results