Fig. 9
Biofilm eradication activity of BiF2_5K7K on S. epidermidis biofilm. A Confocal imaging of preformed S. epidermidis biofilms after treatment with BiF2_5K7K at MBEC50. B The fluorescence intensity ratio of Alexa Flour® 488 stained biofilms. C Live/dead results of S. epidermidis biofilms after treatment with BiF2_5K7K at MBEC50. Live cells stained with SYTO 9 (green) while dead cells stained with propidium iodide (red). D The fluorescence intensity ratios of live/dead cells analysed by ZEN 2.1. The presented data represents the mean ± SD derived from a at least three independent experiments. Statistical significance is indicated by *p-value < 0.05, **p-value < 0.01, ***p-value < 0.001, and ****p-value < 0.0001, highlighting the presence of notable differences in the findings