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Table 1 Antimicrobial susceptibility testing of mcr-8-harboring isolates and their transconjugants

From: Co-existence of two plasmids harboring transferable resistance-nodulation-division pump gene cluster, tmexCD1-toprJ1, and colistin resistance gene mcr-8 in Klebsiella pneumoniae

Antimicrobials

MIC (mg/L) of druga

KP26

KP26/J53

KP29

KP29/J53

J53

CZO

 > 128

4

 > 128

4

4

MOX

2

0.25

2

0.25

0.25

LVX

 > 32

0.06

 > 32

0.06

0.06

ATM

64

0.125

64

0.125

0.125

CRO

 > 64

0.06

 > 64

0.06

0.06

FEP

16

 ≤ 0.015

16

 ≤ 0.015

 ≤ 0.015

AMK

 > 128

2

 > 128

2

2

CZA

0.5/4

0.25/4

0.5/4

0.25/4

0.25/4

CAZ

64

0.25

64

0.25

0.25

CSL

64/32

0.25/0.125

64/32

0.125/0.06

0.125/0.06

ETP

0.25

0.015

0.25

0.015

0.015

CIP

 > 32

 ≤ 0.004

 > 32

 ≤ 0.004

 ≤ 0.004

MEM

0.03

0.03

0.03

0.03

0.03

IMP

0.125

0.25

0.125

0.25

0.25

TGC

8

0.06

8

 ≤ 0.03

0.125

PMB

4

4

4

2

1

CST

8

4

4

4

1

  1. aCZO cefazolin, MOX, latamoxef, LVX levofloxacin, ATM aztreonam, CRO ceftriaxone, FEP cefepime, AMK amikacin, CZA ceftazidime-avibactam, CAZ ceftazidime, CSL cefoperazone-sulbactam, ETP ertapenem, CIP ciprofloxacin, MEM meropenem, IPM imipenem, TGC tigecycline, PMB polymyxin B, CST colistin
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Annals of Clinical Microbiology and Antimicrobials

ISSN: 1476-0711

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