Co-existence of two plasmids harboring transferable resistance-nodulation-division pump gene cluster, tmexCD1-toprJ1, and colistin resistance gene mcr-8 in Klebsiella pneumoniae

Table 2 Features of the isolates

Isolate	Source	DNA types	AMR gene	MLST/plasmid replicon	DNA size(bp)
KP26	Chicken	Chromosome	bla_SHV-182, fosA, oqxB, oqxA	ST11	5,252,651
		pKP26-tmexCD1	aph(6)-Id, aph(3')-Ia, aph(3'')-Ib, aadA1, aadA2b, armA, bla_DHA-1, msr(E), mph(E), cmlA1, qnrB4, sul1, sul3, tmexD1, toprJ1, tmexC1	IncFIB(Mar)/IncHI1B	271,379
		pKP26-mcr8	mcr-8	IncFIA/IncFII	101,185
		pKP26-3	aac(3)-IId, aadA16, aph(6)-Id, aph(3')-Ia, aph(3'')-Ib, aac(6')-Ib-cr, mph(A), ARR-3, sul1, sul2, tet(A), dfrA27	IncFIA,IncQ1,IncR	83,074
		pKP26-4	bla_CTX-M-15, bla_TEM-1B, qnrS1	–^a	72,637
KP29	Chicken	Chromosome	bla_SHV-182, fosA, oqxB, oqxA,	ST11	5,253,463
		pKP29-tmexCD1	aph(6)-Id, aph(3')-Ia, aph(3'')-Ib, aadA1, aadA2b, armA,bla_DHA-1, msr(E), mph(E), cmlA1, qnrB4, sul1, sul3, tmexD1, toprJ1, tmexC1	IncFIB(Mar)/IncHI1B	271,379
		pKP29-2	floR, qnrB52, sul1, tet(A)	IncFIB	131,420
		pKP29-mcr8	mcr-8	IncFIA/IncFII	101,185
		pKP29-4	aac(3)-IId, aadA16, aph(6)-Id, aph(3')-Ia, aph(3'')-Ib, aac(6')-Ib-cr, mph(A), ARR-3, sul1, sul2, tet(A), dfrA27	IncFIA,IncQ1,IncR	83,068
		pKP29-5	bla_CTX-M-15, bla_TEM-1B, qnrS1	–^a	72,637

ISSN: 1476-0711