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Table 2 Summary of radiologic and microbiologic investigations over 10 years of follow-up

From: Long-term successfull management of recurrent episodes of nontuberculous mycobacterial infection in an apparently healthy Chinese woman

Date

Event

Radiology^

Microbiology

2011

Disseminated Mycobacterium szulgai

CT/MRI/PET: lymph nodes, skeletal and lung involvement

Latero-cervical lymph node biopsy and blood cultures: Mycobacterium szulgai

(S-RIF, S-EMB, S-MXF, S-CAM, S-AMK, S-LZD, R-DOXI, R-SXT)

2014

Disseminated MAC

CT/MRI: lymph nodes, skeletal, lung, liver and spleen involvement

CT/MRI (+ 7 months): worsening of vertebral lesions

Vertebral biopsy: Mycobacterium avium complex (R-LZD, R-MXF, S-CAM)

2018

Suspected relapse of dNTM

CT/PET: recurrence of thoracic lymphadenopathies

No documented NTM on bronchoalveolar lavage, sputum, blood, stool and urines

2020

Suspected relapse/recurrence of dNTM

CT/MRI/PET: lymph nodes, spleen and skeletal involvement

No documented NTM on bone marrow aspiration, latero-cervical lymph node biopsy, sputum, blood, stool and urines

  1. Abbreviations MAC: mycobacterium avium complex; RIF: rifampicin; EMB: ethambutol; MXF: moxifloxacin; CAM: clarithromycin; AMK: amikacin; LZD: linezolid; DOXI: doxycycline; SXT: trimethoprim/sulfamethoxazole; R: resistant; S: susceptible; dNTM: disseminated nontuberculous mycobacteria; CT: computer tomography; MRI: magnetic resonance imaging; PET: positron emission tomography