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Table 1 Demographic and clinical characteristics of patients with mucormycosis

From: Clinical characteristics and mortality of mucormycosis in hematological malignancies: a retrospective study in Eastern China

Variables

All(n = 50)

n(%)

Survivors(n = 13)

n(%)

Non-survivors(n = 37)

n(%)

P value

Age (years)

39.98 ± 18.52

38.46 ± 20.71

40.51 ± 17.97

0.692

Male sex

26(52.0)

10(76.9)

16(43.2)

0.037

Underlying diseases

    

Acute myeloid leukaemia

23(46.0)

5(38.5)

18(48.6)

0.526

Acute lymphoblastic leukaemia

8(16.0)

3(23.1)

5(13.5)

0.712

Myelodysplastic syndrome

8(16.0)

0(0.0)

8(21.6)

0.165

Recurrent aplastic anemia

8(16.0)

4(30.8)

4(10.8)

0.212

Chronic myeloid leukemia

2(4.0)

1(7.7)

1(2.7)

0.456

Primary myelofibrosis

1(2.0)

0(0.0)

1(2.7)

1.000

Underlying diseases statusa

25(50.0)

5(38.5)

20(54.1)

0.333

Comorbidityb

    

Hypertension

8(16.0)

3(23.1)

5(13.5)

0.712

Cerebral infarction

3(6.0)

0(0.0)

3(8.1)

0.558

Hepatitis B

2(4.0)

1(7.7)

1(2.7)

0.456

Othersc

3(6.0)

2(15.4)

1(2.7)

0.849

Laboratory data

    

White blood cell (× 109/L)

1.86 ± 2.35

2.57 ± 2.70

1.61 ± 2.19

0.211

Neutrophil (× 109/L)

1.20 ± 1.94

2.15 ± 2.70

0.84 ± 1.47

0.037

Hemoglobin(g/L)

63.94 ± 17.78

62.69 ± 15.39

64.35 ± 18.73

0.776

Blood platelet (× 1012/L)

23.58 ± 17.96

32.62 ± 25.53

20.41 ± 13.48

0.121

Neutrophil count <0.5 × 109/L

30(60.0)

7(53.8)

23(63.2)

0.599

Duration of neutropenia (day)

17.87 ± 12.914

14.36 ± 13.171

18.94 ± 12.828

0.837

Haematopoietic stem cell

transplantation

15(30.0)

3(23.1)

12(32.4)

0.778

Prior voriconazole

36(72.0)

5(38.5)

31(83.8)

0.006

Number of chemotherapy

3.38 ± 3.428

2.38 ± 2.755

3.73 ± 3.603

0.397

  1. a The number of patiens with active hematological malignancies
  2. b A given subject may have had one or more comorbid illnesses
  3. c Includes diabetes mellitus(1), pulmonary emphysema(1), syphilis(1)