Variables | All(n = 50) n(%) | Survivors(n = 13) n(%) | Non-survivors(n = 37) n(%) | P value |
---|---|---|---|---|
Age (years) | 39.98 ± 18.52 | 38.46 ± 20.71 | 40.51 ± 17.97 | 0.692 |
Male sex | 26(52.0) | 10(76.9) | 16(43.2) | 0.037 |
Underlying diseases | Â | Â | Â | Â |
Acute myeloid leukaemia | 23(46.0) | 5(38.5) | 18(48.6) | 0.526 |
Acute lymphoblastic leukaemia | 8(16.0) | 3(23.1) | 5(13.5) | 0.712 |
Myelodysplastic syndrome | 8(16.0) | 0(0.0) | 8(21.6) | 0.165 |
Recurrent aplastic anemia | 8(16.0) | 4(30.8) | 4(10.8) | 0.212 |
Chronic myeloid leukemia | 2(4.0) | 1(7.7) | 1(2.7) | 0.456 |
Primary myelofibrosis | 1(2.0) | 0(0.0) | 1(2.7) | 1.000 |
Underlying diseases statusa | 25(50.0) | 5(38.5) | 20(54.1) | 0.333 |
Comorbidityb | Â | Â | Â | Â |
Hypertension | 8(16.0) | 3(23.1) | 5(13.5) | 0.712 |
Cerebral infarction | 3(6.0) | 0(0.0) | 3(8.1) | 0.558 |
Hepatitis B | 2(4.0) | 1(7.7) | 1(2.7) | 0.456 |
Othersc | 3(6.0) | 2(15.4) | 1(2.7) | 0.849 |
Laboratory data | Â | Â | Â | Â |
White blood cell (× 109/L) | 1.86 ± 2.35 | 2.57 ± 2.70 | 1.61 ± 2.19 | 0.211 |
Neutrophil (× 109/L) | 1.20 ± 1.94 | 2.15 ± 2.70 | 0.84 ± 1.47 | 0.037 |
Hemoglobin(g/L) | 63.94 ± 17.78 | 62.69 ± 15.39 | 64.35 ± 18.73 | 0.776 |
Blood platelet (× 1012/L) | 23.58 ± 17.96 | 32.62 ± 25.53 | 20.41 ± 13.48 | 0.121 |
Neutrophil count <0.5 × 109/L | 30(60.0) | 7(53.8) | 23(63.2) | 0.599 |
Duration of neutropenia (day) | 17.87 ± 12.914 | 14.36 ± 13.171 | 18.94 ± 12.828 | 0.837 |
Haematopoietic stem cell transplantation | 15(30.0) | 3(23.1) | 12(32.4) | 0.778 |
Prior voriconazole | 36(72.0) | 5(38.5) | 31(83.8) | 0.006 |
Number of chemotherapy | 3.38 ± 3.428 | 2.38 ± 2.755 | 3.73 ± 3.603 | 0.397 |