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Table 1 Demographic and clinical characteristics of the included patients

From: Nanopore-targeted sequencing (NTS) for intracranial tuberculosis: a promising and reliable approach

Characteristic

Overall(n = 122)

Intracranial tuberculosis (n = 100)

Other brain diseases

(n = 22)

P-value

Age

52.0[31.0,64.8]

50.0[30.0,64.0]

56.0[48.0,65.0]

0.190

Gender

   

0.275

 Male

62(50.8)

48(48.0)

14(63.6)

 

 Female

60(49.2)

52(52.0)

8(36.4)

 

Fever

   

0.088

 Yes

84(68.9)

65(65.0)

19(86.4)

 

 No

38(31.1)

35(35.0)

3(13.6)

 

Headache

   

0.030

 Yes

66(54.1)

49(49.0)

17(77.3)

 

 No

56(45.9)

51(51.0)

5(22.7)

 

Dizziness

   

< 0.001

 Yes

47(38.5)

30(30.0)

17(77.3)

 

 No

75(61.5)

70(70.0)

5(22.7)

 

Nausea and vomiting

   

0.001

 Yes

30(24.6)

18(18.0)

12(54.5)

 

 No

92(75.4)

82(82.0)

10(45.5)

 

Consciousness disorder

   

0.986

 Yes

14(11.5)

12(12.0)

2(9.1)

 

 No

108(88.5)

88(88.0)

20(90.9)

 

Hypomnesia

   

0.550

 Yes

10(8.2)

7(7.0)

3(13.6)

 

 No

112(91.8)

93(93.0)

19(86.4)

 

Cerebral infarction

   

0.056

 Yes

34(27.9)

32(32.0)

2(9.1)

 

 No

88(72.1)

68(68.0)

20(90.9)

 

Cerebral hemorrhage

   

0.950

 Yes

3(2.5)

3(3.0)

0(0.0)

 

 No

119(97.5)

97(97.0)

22(100.0)

 

Image type

   

0.080

Meningeal

56(45.9)

41(41.0)

15(68.2)

 

Brain parenchymal

31(25.4)

27(27.0)

4(18.2)

 

Mixed

35(28.7)

32(32.0)

3(13.6)

 

CSF pressure(/cmH2O)

15.0[10.0,18.4]

14.0[10.0,17.0]

23.0[16.0,34.0]

< 0.001

Cell count (/*106)

6.0[1.0,60.0]

4.0[1.0,27.0]

138.5[10.0,232.8]

< 0.001

Protein(mg/L)

342.0[156.0,758.3]

422.5[193.0,816.5]

179.0[100.8,273.3]

0.004

Glucose(mmol/L)

3.5[2.8,4.1]

3.5[2.9,4.1]

3.5[2.7,3.7]

0.478

Chloride(mmol/L)

123.0[116.0,126.0]

123.0[116.0,126.0]

121.0[113.3,125.5]

0.209

ADA(U/L)

1.0[0.0,4.0]

1.0[0.0,4.0]

4.0[0.0,5.0]

0.160