Nanopore-targeted sequencing (NTS) for intracranial tuberculosis: a promising and reliable approach

Table 3 Diagnostic accuracy of the five tests for diagnosing intracranial tuberculosis and other brain diseases

Test	Meningeal		Brain parenchymal		Mixed		Overall
Test	χ²	P-value	χ²	P-value	χ²	P-value	χ²	P-value
NTS	0.408	0.523	0.724	0.439	0.299	0.675	1.375	0.241
Xpert MTB/RIF	20.287	< 0.001	15.242	0.002	2.933	0.143	37.937	< 0.001
MTB culture	20.287	< 0.001	11.215	0.007	17.371	0.002	48.207	< 0.001
PCR	20.287	< 0.001	15.242	0.002	17.371	0.002	51.549	< 0.001
AFB smear	23.077	< 0.001	15.242	0.002	17.371	0.002	55.217	< 0.001

ISSN: 1476-0711