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Table 1 Characteristic of patients in AMRT + and AMRT- group

From: Clinical and metagenomic predicted antimicrobial resistance in pediatric critically ill patients with infectious diseases in a single center of Zhejiang

Group

AMRT+ (N = 44) a

AMRT- (N = 69) a

P-value

Gender-boy, n (%)

25 (56.82%)

41 (59.42%)

0.7844

Age, mean ± SD

80.34 ± 55.10

71.20 ± 50.07

0.4119

Immunosuppression, n (%)

22 (50%)

20 (28.99%)

0.0242

Underlying disease, n (%)

31 (70.45%)

28 (40.58%)

0.0019

Leukemia, n (%)

17 (38.64%)

12 (17.39%)

0.0117

Symptoms

   

 Fever, n (%)

42 (95.45%)

59 (85.51%)

0.0942

 Cough, n (%)

17 (38.64%)

15 (21.74%)

0.0519

Clinical feature, mean ± SD

   

 BMI

14.80 ± 2.58

16.12 ± 3.53

0.0411

 pSOFA

5.27 ± 3.31

4.1 ± 2.89

0.0466

 PRISM

12.39 ± 10.23

4.81 ± 5.67

< 0.0001

 PCIS

85.77 ± 7.75

88.75 ± 8.62

0.0405

 WBC

8.33 ± 9.17

12.12 ± 30.43

0.4042

 NEUT

7.18 ± 7.18 (n = 39)

6.41 ± 5.8 (n = 66)

0.6677

 LY

1.36 ± 1.72 (n = 39)

1.69 ± 1.92 (n = 66)

0.3990

 NEUT%

69.56 ± 22.53 (n = 39)

65.39 ± 22 (n = 67)

0.4120

 LY%

30.53 ± 70.20 (n = 39)

24.84 ± 18.12 (n = 67)

0.4887

 PLT

173.27 ± 161.87

212.32 ± 164.9

0.2195

 HBG

111.45 ± 121.47

107.07 ± 20.59

0.7715

 BUN

4.93 ± 3.53

4.93 ± 3.79

0.9183

 Cr

24.77 ± 12.13

42.61 ± 72.66

0.0975

 TBIL

20.09 ± 27.42

12.93 ± 18.34

0.2055

 PaO2/FiO2

269.23 ± 135.18

306.73 ± 132.25

0.1618

 CRP

67.69 ± 80.16

29.18 ± 46

0.0025

 PCT

10.83 ± 27.49

9.82 ± 50.56 (n = 67)

0.9259

 γ-IFN

5.78 ± 6.24

184.34 ± 987.38 (n = 66)

0.2392

 IL-6

728.61 ± 1783.29 (n = 40)

646.32 ± 2934.9 (n = 66)

0.9581

 IL-10

360.54 ± 990.91

291.14 ± 1611.67 (n = 66)

0.7807

LOHS, mean ± SD

48.7 ± 43.39

16.46 ± 12.11

< 0.0001

ICU, mean ± SD

23.05 ± 31.89

8.72 ± 7.83

0.0005

Mortality rate, n (%)

8 (18.18%)

7 (10.14%)

0.2195

  1. a Data on clinical indicators were missing for some patients, and “(n=)” indicated the number of people to be tested. BMI: Body Mass Index; pSOFA: Pediatric sequential organ failure assessment; PRISM: pediatric risk of mortality; PCIS: pediatric critical illness score; WBC: white blood cell; NEUT: neutrophil; LY: lymphocyte; NEUT%: neutrophil percentage; LY%: lymphocyte percentage; PLT: platelet; HBG: hemoglobin; BUN: blood urea nitrogen; Cr: creatinine; TBIL: total bilirubin; PaO2/FiO2: the ratio of arterial oxygen partial pressure to fractional inspired oxygen; CRP: C-reactive protein; PCT: procalcitonin; γ-IFN: Interferon-γ; IL-6: Interleukin 6; IL-10: Interleukin 10; LOHS: length of hospital stays; ICU: length of ICU stays