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Table 3 The performance of mNGS in the prediction of cephalosporins, carbapenems and sulfonamides

From: Clinical and metagenomic predicted antimicrobial resistance in pediatric critically ill patients with infectious diseases in a single center of Zhejiang

Antibiotic

TP

FP

FN

TN

Sensitivity

Specificity

PPV

NPV

Accuracy

cephalosporins

12

11

8

8

60.00%

42.11%

52.17%

50.00%

51.28%

carbapenems

8

7

4

13

66.67%

65.00%

53.33%

76.47%

65.60%

sulfonamides

3

1

17

12

15.00%

92.31%

75.00%

41.38%

45.45%

  1. TN: True negative, TP: True positive, FN: False negative, FP: False positive, PPV: positive predictive value, NPV: negative predictive value. Accuracy=(TP + TN)/(TP + TN + FP + FN)