Fig. 8
From: Drug susceptibility testing of Nocardia spp. using the disk diffusion method

Distribution of Nocardia isolates (n = 134) according to the inhibition diameter (mm) measured around the tobramycin disk and their minimal inhibitory concentration (MIC) for tobramycin determined by broth microdilution using Sensititre™ Myco RAPMYCOI after 72 h incubation. Shades of green: strains categorized as susceptible; orange: strains categorized as intermediate; shades of red: strains categorized as resistant according to Clinical Laboratory Standard Institute critical concentrations. Bold dotted line: critical inhibition diameter according to Youden index and the point closest to the upper left-hand corner of the ROC curve (ROC01) = 19 mm (inhibition diameter ≤ 19: tobramycin I or R; inhibition diameter > 19: tobramycin S)