Table 1 Clinical characteristics of 26 patients infected with ColR-CRKP isolates
Clinical Characteristics | Results |
|---|---|
Mean age (Min-Max) | 51.3 (16–86) |
Gender | n (%) |
Male | 16 (61.5) |
Female | 10 (38.5) |
Admission Unit | n (%) |
Intensive care unit (ICU) | 9 (34.6) |
Neurosurgical ICU | 5 (19.2) |
Haematology ward | 3 (11.5) |
Neurology ICU | 2 (7.7) |
Rehabilitation medicine | 2 (7.7) |
Respiratory ICU | 1 (3.8) |
Emergency ICU | 1 (3.8) |
Others | 3 (11.5) |
Hospitalization days median (Min-Max) | 51.3 (13–231) |
Underlying disease | n (%) |
Brain disease | 15 (57.7) |
Severe pneumonia | 4 (15.4) |
Hematologic malignancy | 3 (11.5) |
Liver disease | 2 (7.7) |
Kidney disease | 2 (7.7) |
Healthcare-associated infections | n (%) |
Lower respiratory tract infection | 10 (38.5) |
Urinary tract infection | 7 (26.9) |
Ventilator-associated pneumonia | 4 (15.4) |
Blood stream infection | 3 (11.5) |
Central nervous system infection | 2 (7.7) |
Prior exposure to antimicrobials | n (%) |
Carbapenems | 20 (77.0) |
beta-lactam/beta-lactamase inhibitor | 17 (65.4) |
Polymyxin B | 14 (53.8) |
Fluoroquinolone | 7 (26.9) |
Cephalosporins | 7 (26.9) |
Tigecycline | 6 (23.1) |
Aminoglycosides | 4 (15.4) |
Ceftazidime-avibactam | 1 (3.8) |
Outcomes | n (%) |
Improved | 16 (61.5) |
Gave up | 7 (26.9) |
Death | 3 (11.5) |