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Table 2 Antibacterial resistance profiles of bacteria and pathogens isolated from blood culture in patients from Eritrea, 2014–2022

From: Major blood stream infection-causing bacterial pathogens, antimicrobial resistance patterns and trends: a multisite retrospective study in Asmara, Eritrea (2014–2022)

Antibiotic

Overall R (%)1

E. coli

R (%)

Klebsiella spp. R (%)

Enterobacter

R (%)

Pseudomonas spp R (%)1

Citrobacter

R (%)1

Salmonella spp R (%)

Other GNB R (%)1

S. aureus

R (%)

CoNs

R (%)

Aminoglycosides

 Amikacin

27(8.6)

7(11.9%)

5(4.9)

2(7.4)

5(15.6)

4(9.1)

1 (3.7)

3(11.1)

-

-

 Gentamicin

363(62.5)

36(55.4)

97(83.7)

16(57.1)

18(54.5)

39(81.2)

17(54.8)

22(71.0)

14(31.1)

104(56.5)

Anti folate

 TMP-SMZ

261(71.7)

47(75.8)

77(74.8)

19(67.9)

18(54.5)

36(76.6)

20(69.0)

17(77.3)

26(68.4)

1(50)

Cephalosporins

 Cephalexin 3rd

273(83.7)

44(69.8)

92(86.8)

25(89.3)

25(78.1)

45(95.7)

23(79.3)

-

-

-

 Ceftazidime3rd

233(68.5)

39(60.9)

84(74.3)

14(48.3)

22(66.7)

36(76.6)

23(74.2)

15(65.2)

-

-

 Ceftriaxone 3rd

251(73.0)

39(60.9)

95(81.5)

22(75.9)

16(48.5)

40(85.1)

21(67.7)

18(78.3)

-

-

Quinolone

 Nalidixic acid 1st

112(34.5)

32(52.5)

20(18.7)

7(25.9)

19(57.6)

19(40.4)

4(13.8)

9(47.4)

2(100.0)

 

 Ciprofloxacin 2nd

115(29.4)

30(46.9)

21(18.8)

9(31.0)

8(25.0)

11(22.9)

2(6.5)

15(50.0)

19(45.2)

0(0)

Phenicols

 Chloramphenicol

188(32.6)

17(26.2)

46(40.7)

14(48.3)

20(62.5)

23(50)

18(58.1)

17(48.6)

10(21.7)

23(12.8)

Tetracyclines

 Tetracycline

213(57.0)

41(66.1)

50(48.1)

15(55.6)

23(71.9)

28(60.9)

19(65.5)

-

18(43.9)

1(50.0)

Glycopeptide

 Vancomycin

80(32.8)

-

-

-

-

-

-

-

13(27.7)

66(35.5)

Lincosamides

 Clindamycin

6(12.8)

-

-

-

-

-

-

-

6(14.3)

0.0)

Beta-Lactams

 Penicillin

206(90.7)

-

-

-

-

-

-

-

38(86.4)

168 (92.3)

 Oxacillin

208(91.2)

-

-

-

-

-

-

-

37(80.4)

171(94.5)

 Ampicillin

333(94.3)

61(92.4)

112(95.7)

29(96.7)

31(93.9)

45(93.8)

25(80.6)

30(83.3)

-

-

Macrolides

 Erythromycin

18(42.9)

-

-

-

-

-

-

 

18(42.9)

0

Other

 

 Nitrofurantoin

155(42.2)

12(19.0)

 

14(51.9)

25(80.6)

31(66.0)

4(13.8)

16(72.7)

4(9.8)

1(33.3)

  1. Abbreviation: Overall R: Overall resistance; GNB– Gram-Negative Bacteria; GNP– Gram positive bacteria, CoNs: coagulase negative staphylococcus; TMP-SMZ: Trimethoprim sulfamethoxazole;
  2. Description: Other GNB: Other gram-negative bacteria