Table 3 Resistance patterns for specific pathogens for selected antibiotics per year
Isolates | < 2016 n(%) | 2017–2018 n(%) | 2019–2020 n(%) | > 2020 (%) | P value (χ2)b |
|---|---|---|---|---|---|
Klebsiella spp., | |||||
Ampicillin | 21 (91.3) | 14(100) | 37(100) | 40(100) | 0.234 (8.05)b |
Ceftazidime | 17(73.9) | 13(92.9) | 32(88.9) | 22(55.0) | 0.015 (15.71)b |
Ceftriaxone | 19(76.0) | 14(93.3) | 32(86.5) | 30(75.0) | 0.212 (8.38) |
Ciprofloxacin | 0 (0) | 4(26.7) | 11(29.7) | 6(15.0) | < 0.001 (31.9)b |
TMP-SMZ | 10(83.3) | 11(78.6) | 33(89.2) | 23(57.5) | 0.020 (15.05) |
Gentamicin | 22(88) | 14(93.3) | 34(91.9) | 27(69.2) | 0.105 (10.51) |
Tetracycline | 1(6.2) | 8(61.5) | 25(71.4) | 16(40.0) | 0.002 (21.25)b |
Chloramphenicol | 16(66.7) | 9(64.3) | 12(34.3) | 9(22.5) | 0.003(19.7)b |
Escherichia coli | |||||
Ampicillin | 5(83.3) | 6(100) | 23(100) | 27(93.1) | 0.444 (5.82) |
Ceftazidime | 3(50) | 5(83.3) | 17(73.9) | 14(35.9) | 0.325 (6.95) |
Ceftriaxone | 2 (33.3) | 4(66.7) | 14(60.9) | 19(65.5) | 0.480 (5.51) |
Ciprofloxacin | 1(20) | 4(57.1) | 9(39.1) | 16(55.2) | 0.384 (6.36) |
TMP-SMZ | 3(100) | 6(85.7) | 18(78.3) | 20(69) | 0.542(2.15) |
Gentamicin | 2(33.3) | 4(57.1) | 16(69.6) | 14(48.3) | 0.140 (9.65) |
Tetracycline | 1(25) | 4(57.1) | 17(73.9) | 19(67.9) | 0.25(7.84) |
Chloramphenicol | 2(28.6) | 2(28.6) | 8(36.4) | 5(17.2) | 0.489 (2.42) |
Pseudomonas aeruginosa | |||||
Ampicillin | 2(100) | 4(80.0) | 16(94.1) | 9(100) | 0.351(6.69) |
Ceftazidime | 1(50) | 4(80.0) | 14(82.4) | 3(33.3) | |
Ceftriaxone | 1(50) | 4(80) | 7(41.2) | 4(44.4) | 0.409 (6.13) |
Ciprofloxacin | 0 (0) | 1(25.0) | 4(23.5) | 3(33.3) | 0.928 (1.91) |
TMP-SMZ | 2(100) | 2(40.0) | 7(41.2) | 7(77.8) | 0.315 (7.06) |
Gentamicin | 1(50) | 3(60) | 8(47.1) | 6(66.7) | 0.946(1.69) |
Tetracycline | 0 (0) | 3(60) | 12(70.6) | 8(88.9) | 0.357(6.62) |
Chloramphenicol | 1(50) | 3(60) | 10(62.5) | 6(66.7) | 0.642(4.26) |
CoNs | |||||
Vancomycin | 10(17.2) | 1(6.7) | 12(24.5) | 43(65.2) | < 0.001 (46.2) |
Oxacillin | 54(90) | 11(100) | 48(98.0) | 58(95.1) | 0.361(6.59) |
Gentamicin | 23(38.3) | 9(69.2) | 47(25.5) | 64(34.8) | < 0.001(24.46) |
Chloramphenicol | 3(5.5) | 3(20) | 7(14.3) | 10 (16.7) | 0.515 (5.23) |
Staphylococcus aureus | |||||
Oxacillin/MRSA | 9(90) | 7(87.5) | 10(71.4) | 11(78.6) | 0.330(5.00) |
Ciprofloxacin | 0 (0) | 4(57.1) | 10(71.4) | 5(33.3) | 0.045(12.87) b |
Vancomycin | 2(20) | 1(12.5) | 3(21.4) | 7(46.7) | 6.97(0.324) |
TMP-SMZ | 3(100) | 4(57.1) | 10(71.4) | 9(64.3) | 0.58 (1.97) |
Erythromycin | 1(20) | 6(75.0) | 6(42.9) | 5(33.3) | 0.29(7.37) |
Clindamycin | 2(33.3) | 0(0) | 2(14.3) | 2(13.3) | 0.554(4.92) |
Total | |||||
Ampicillin | 38(84.4) | 38(97.4) | 111(96.5) | 146(94.8) | 0.012(16.29) |
Ceftazidime | 28(63.6) | 29(80.6) | 97(87.4) | 79(53.0) | < 0.001(40.36) b |
Ceftriaxone | 28(59.6) | 31(86.1) | 84(75.0) | 108(72.5) | 0.039(13.3) |
Ciprofloxacin | 3(6.7) | 17(36.2) | 49(38.3) | 46(26.9) | < 0.001(43.66) |
TMP-SMZ | 19(76.0) | 32(69.6) | 100(78.7) | 110(66.3) | 0.062(12.00) |
Gentamicin | 56(47.9) | 43(70.5) | 127(73.8) | 137(59.3) | < 0.001(32.8) |
Tetracycline | 5(15.2) | 24(52.2) | 85(67.5) | 99(58.6) | < 0.001(38.76) |
Chloramphenicol | 28(24.8) | 29(46.0) | 63(36.8) | 68(29.7) | 0.018(15.3) |