Table 2 Minimum inhibitory concentrations (MICs) of NTM against 5 antimycobacterial drugs
Patient | Species identified by tNGS/WGS | MIC (µg/ml) | ||||
|---|---|---|---|---|---|---|
AMI | CIP* | MXF | CLA | LZD | ||
CZ281/19 | M. neoaurum/ M. neoaurum | 0.5 (S) | 0.5 (S) | NE | 0.25 (S) | NE |
CZ377/22 | M. neoaurum/ M. neoaurum | 0.5 (S) | 0.5 (S) | NE | NE | 0.25 (S) |
CZ573/23 | M. neoaurum/ M. neoaurum | 0.5 (S) | 0.5 (S) | 0.125 (S) | 0.5 (S) | 0.5 (S) |
SVK95/23 | M. neoaurum/ M. neoaurum | 0.125 (S) | 1 (S) | 0.125 (S) | 0.25 (S) | 0.25 (S) |
SVK407/23 | M. neoaurum/NP | 0.5 (S) | 0.5 (S) | 0.125 (S) | 0.125 (S) | 0.5 (S) |
SVK408/23 | M. neoaurum/NP | 0.5 (S) | 1 (S) | 0.5 (S) | 0.25 (S) | 0.5 (S) |
SVK432/23 | M. neoaurum/NP | 0.5 (S) | 0.5 (S) | 0.125 (S) | 0.25 (S) | 0.25 (S) |
SVK231/23 | M. neoaurum/NP | 0.125 (S) | 0.5 (S) | NE | 0.5 (S) | 0.25 (S) |
CZ118/21 | M. intracellulare - M. kumamotonense/ Tsukamurella tyrosinosolvens | 0.5 (S) | 0.5 (S) | 0.125 (S) | 1.0 (S) | 4.0 (S) |
CZ126/21 | M. kumamotonense/ M. kumamotonense | 32.0 (I) | 16.0 (R) | 4.0 (R) | 0.5 (S) | 16.0 (I) |
CZ19/23 | M. kumamotonense/ M. kumamotonense | 2.0 (S) | 2.0 | NE | NE | NE |
CZ276/23 | M. kumamotonense/ M. kumamotonense | 1.0 (S) | 1.0 | 0.5 (S) | 1.0 (S) | 4.0 (S) |
CZ421/23 | M. kumamotonense/ M. kumamotonense | 4.0 (S) | 4.0 | 2.0 (I) | 4.0 (S) | 32.0 (R) |
CZ131/21 | M. intracellulare - M. setense/ potential novel species | 4.0 (S) | 0.5 (S) | 0.125 (S) | > 32.0 (R) | 8.0 (S) |
CZ614/21 | M. chimaera - M. massiliense/ Streptococcus mitis (TYGS), M. branderi (NTMprofiler v0.2.2; 0.4.0) | 32.0 (I) | 16.0 (R) | 0.5 (S) | 1.0 (S) | 32.0 (R) |
CZ356/20 | M. chimaera - M. vulneris/ M. intracellulare | 4.0 (S) | 4.0 (R) | 0.5 (S) | 0.5 (S) | 16.0 (I) |
CZ457/20 | M. tuberculosis - M. avium/ M. tuberculosis - M. avium | NE | NE | NE | NE | NE |
CZ523/21 | M. setense/ M. setense | 0.5 (S) | 0.5 (S) | 0.125 (S) | 4.0 (S) | 4.0 (S) |
CZ265/20 | M. arupense/ potential novel species | 2.0 (S) | 1.0 (S) | 0.5 (S) | 0.125 (S) | 0.25 (S) |
CZ18/23 | M. arupense/NP | 8.0 (S) | 8.0 (R) | NE | NE | NE |
SVK397/23 | M. arupense/NP | 4.0 (S) | 1.0 (S) | 0.25 (S) | 0125 (S) | 0.5 (S) |
CZ118/23 | NTM not detected/ M. celatum | 0.5 (S) | 2.0 (S) | 0.25 (S) | 0.5 (S) | 32.0 (R) |
CZ468/21 | NTM not detected/ potential novel species | 1.0 (S) | 1.0 (S) | 1.0 (S) | 0.5 (S) | 0.5 (S) |
SVK300/23 | M. arupense - M. yongonense/NP | 4.0 (S) | 1.0 (S) | NE | NE | 0.25 (S) |
CZ111/20 | M. fluoranthenivorans/ M. fluoranthenivorans | 0.5 (S) | 0.5 (S) | NE | 0.25 (S) | NE |
SVK403/23 | M. holsaticum/NP | 0.5 (S) | 0.5 (S) | 0.125 (S) | 0.25 (S) | 0.25 (S) |
CZ112/23 | M. lentiflavum/ M. lentiflavum | 0.5 (S) | 0.5 (S) | NE | NE | NE |
SVK1921/23 | M. chimaera/NP | 4.0 (S) | 0.5 (S) | 0.125 (S) | 0.5 (S) | 8.0 (S) |