Fig. 4

Sequencing depth of MTB genome sequences obtained using mNGS and HDA-mNGS. A Coverage depth distribution of MTB genome. From inside to outside shows sequence depths of conventional mNGS of 1X and 3X and HDA-mNGS of 1X and 3X. The vertical text on the right indicates percent values of samples, whereby the circled numbers represent positions within the M. tuberculosis H37Rv sequence. B Heatmap of depth for each sample in 184 antimicrobial resistance locus