Fig. 8

Schematic representation of the therapeutic efficacy workflow for PSK and vancomycin in a murine wound infection model. The wounded mice were challenged with 10⁸ CFU/mL, then treated subcutaneously 2 hpi (the lower panel) or 2 dpi (the upper panel) with PSK vancomycin or PBS. The wound diameter was measured at days 2, 4, 6 and 8. The skin tissues from each group were stained with Hematoxylin and Eosin (H&E) at days 2 and 8 or MTC at day 8 and examined microscopically. Finally, the bacterial count within skin tissues was counted on days 2 and 8