Table 1 Characteristics of specimen, the diagnostics method and the results
From: A pathogen-detection’s odyssey in a case of skull base osteomyelitis: Land ahoy!
Date | Specimen | Culture | Mycobacteria culture | Pan-PCR (fungi) | Pan-PCR (bacteria) | T. gondii-PCR | M. pneumoniae-PCR |
|---|---|---|---|---|---|---|---|
10.11.2020 | Biopsy middle ear | Negative | – | – | – | – | – |
Biopsy mastoid bone | Negative | – | – | – | – | – | |
07.12.2021 | Biopsy posterior tympanotomy | Negative | – | – | – | – | – |
Biopsy mastoid bone | Negative | – | – | - | – | – | |
Biopsy tympanotomy | Negative | – | – | – | – | – | |
Biopsy mastoid bone | Negative* | – | – | – | – | – | |
Swab mastoid bone | Negative | – | – | – | – | – | |
Swab mastoid bone left | Negative | – | – | – | – | – | |
Swab mastoid bone apex | Negative | – | – | – | - | – | |
26.01.2022 | Mastoid bone | Negative* | Negative | Negative | Negative | – | – |
Swab ear left near "electrode" | Negative | – | Negative | Negative | – | – | |
Biopsy medial skull base | Negative* | Negative | Negative | Negative | – | – | |
Biopsy bone medial temporomandibular joint | Negative | – | Negative | Negative | – | – | |
Swab middle ear direction tube* | Negative | – | Negative | Negative | – | – | |
17.06.2022 | Biopsy left sigmoid sinus | Negative* | Negative | Negative | – | Negative | Positive (+/−) |
Biopsy mastoid cavity left | Negative | Negative | Negative | - | Negative | Positive (+) | |
Biopsy middle bone cranial fossa left | Negative | Negative | Negative | Negative | Negative | Negative | |
Biopsy left temporomandibular joint direction | Negative | – | Negative | – | Negative | Positive (++) | |
Biopsy middle ear left | Negative | – | Negative | – | Negative | Positive (+++) |