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Table 1 The characteristics of included patients

From: Mortality and exacerbations in bronchiectasis patients with carbapenem-resistant Pseudomonas aeruginosa isolation: a long-term retrospective cohort study

Variables

All patients (N = 564)

Non-CRPA (N = 421)

CRPA (N = 143)

p-value

Demographics

    

 Age (years), median (IQR)

62.55 (52.50–70.95)

61.50 (52.40–70.20)

64.30 (52.80–73.60)

0.117

 Male

233 (41.31%)

168 (39.90%)

65 (45.45%)

0.244

 BMI (kg/m2)

21.49 (19.20–23.79)

21.50 (19.11–23.83)

21.48 (19.32–23.30)

0.932

Comorbidities

    

 Hypertension

104 (18.44%)

73 (17.34%)

31 (21.68%)

0.248

 Diabetes

70 (12.41%)

46 (10.93%)

24 (16.78%)

0.066

 COPD

116 (20.57%)

79 (18.76%)

37 (25.87%)

0.069

 Malignant tumors

36 (6.38%)

24 (5.70%)

12 (8.39%)

0.255

 Asthma

32 (5.67%)

20 (4.75%)

12 (8.39%)

0.104

 Connected tissue disease

23 (4.08%)

16 (3.80%)

7 (4.90%)

0.567

 Gastro-oesophageal reflux disease

22 (3.90%)

18 (4.28%)

4 (2.80%)

0.430

Hemoptysis

139 (24.65%)

106 (25.18%)

33 (23.08%)

0.614

BAE

58 (10.28%)

47 (11.16%)

11 (7.69%)

0.238

Antibiotic treatment

515 (91.31%)

389 (92.40%)

126 (88.11%)

0.116

Laboratory Values

    

 WBC (× 10⁹/L), median (IQR)

6.92 (5.31–8.99)

6.75 (5.17–8.74)

7.44 (5.84–9.90)

0.007

 ANC (× 10⁹/L), median (IQR)

4.73 (3.28–6.52)

4.44 (3.11–6.12)

5.60 (4.04–8.13)

< 0.001

 AEC (× 10⁹/L), median (IQR)

0.11 (0.05–0.21)

0.11 (0.06–0.22)

0.09 (0.02–0.18)

0.020

 PLT (× 10⁹/L), median (IQR)

201 (149.5- 263)

199 (149–259)

213 (154–288)

0.152

 Hemoglobin (g/L), median (IQR)

118 (106–132)

120 (109–133)

113 (99–127)

< 0.001

Lengths of hospital stay, median (IQR)

12 (9- 15.5)

11 (9–14)

14 (10–20)

< 0.001

Acute exacerbations*

247 (43.79%)

167 (39.67%)

80 (55.94%)

0.001

  1. IQR: interquartile range; BMI: body mass index; COPD: chronic obstructive pulmonary disease; BAE: bronchial artery embolization; WBC: white blood cell; ANC: absolute neutrophil count; AEC: absolute eosinophil count; PLT: platelet count; * ≥ 2 times within the first year post-discharge