Table 1 Characteristics of the included studies
Last name of first author | Publication year | Study period | Governorate | Setting | Susceptibility test for colistin | Total tested for colistin | No. of colistin-resistant isolates | Isolates chosen for Colistin susceptibility testing | Tested Species | Quality score (Out of 8) |
|---|---|---|---|---|---|---|---|---|---|---|
Shawky [68] | 2015 | NA | Alexandria | Alexandria Main University Hospital | E-test | 65 | 9 | CR | K. pneumoniae | 5 |
Azzab [67] | 2016 | 2014–2015 | Zagazig | Zagazig University Hospital | DD | 37 | 0 | Total | Klebsiella Spp. | 6 |
Alkasaby [66] | 2017 | 2014–2016 | Mansoura | Mansoura University Hospital | E-test | 280 | 9 | Total | A. baumannii | 7 |
Assem [64] | 2017 | 2013 | Cairo | Cairo University Hospital | DD | 50 | 0 | Total | A. baumannii, K. pneumoniae, P. aeruginosa, and E. coli​. | 6 |
Ghonaim [63] | 2017 | 2014–2016 | Zagazig | Zagazig University Hospitals | VITEK-2 | 22 | 0 | ESBL | E. coli, K. pneumoniae, E. cloacae | 6 |
Abdulall [62] | 2018 | 2015–2016 | Cairo | ICU (3 tertiary hospital units) | DD | 57 | 0 | Total | E. cloacae, E. coli, A. baumannii, and P. aeruginosa​ | 6 |
Abdulzahra [61] | 2018 | Jan– Jul 2015 | Cairo | El-Kasr El-Ainy Hospital | BMD | 40 | 2 | CRE | A. baumannii | 7 |
El-Mahallawy [76] | 2018 | 2015 | Cairo | National Cancer Institute | VITEK-2 | 96 | 0 | Total | K. pneumoniae, E. coli | 6 |
El-Masry [60] | 2018 | 2016–2018 | Giza | Giza Chest Hospital | VITEK-2 | 22 | 1 | Total | A. baumannii | 6 |
Awad [59] | 2019 | 2017–2018 | Menoufia | National Liver Institute | VITEK-2 not | 38 | 0 | Total | K. pneumoniae, E. coli, M. morganii. | 6 |
Emara [58] | 2019 | 2017–2018 | Tanta | Tanta University Hospitals | BMD | 61 | 10 | Total | K. pneumoniae, E. coli, P. aeruginosa | 7 |
Mokhtar [57] | 2019 | 2017–2018 | Assiut, Minia | Assiut & Minia University Hospitals | BMD | 100 | 22 | MDR | E. coli | 8 |
Sokkary [56] | 2019 | June 2017– May 2018 | Zagazig | Zagazig University Hospitals | BMD | 1,218 | 34 | MDR | E. coli, K. pneumoniae. | 8 |
Zafer [55] | 2019 | Jan 2016– June 2017 | Cairo | National Cancer Institute | BMD | 450 | 40 | Total | K. pneumoniae, E. coli | 8 |
Basha [53] | 2020 | 2017 | Giza | Kasr El Aini Hospital & El Borg Laboratory | BMD | 100 | 0 | Total | P. aeruginosa | 8 |
El-Baky [72] | 2020 | 2016–2017 | Minia | Minia University Hospital | AD | 72 | 16 | MDR | P. aeruginosa | 6 |
Fam [52] | 2020 | 2015–2016 | Giza | Theodor Bilharz Research Institute | BMD | 17 | 9 | CR | A. baumannii | 7 |
Rabie [51] | 2020 | Jan - Aug 2019 | Zagazig | Zagazig University Hospitals | BMD | 200 | 24 | Total | E. coli, K. pneumoniae | 8 |
Raheel [50] | 2020 | Nov 2016 - Dec 2018 | Ismailia | Suez Canal University Hospitals | BMD | 53 | 21 | CR | E. coli, K. pneumoniae | 7 |
Shabban [49] | 2020 | June - Dec 2019 | Cairo | Ain Shams University Hospital | E-test | 60 | 4 | MDR | K. pneumoniae, P. aeruginosa, A. baumannii, E. coli | 6 |
El-Mokhtar [48] | 2021 | 2017–2019 | Assiut | Assiut University Hospital | BMD | 140 | 21 | Total | E. coli | 8 |
Elshimy [47] | 2021 | 2018–2019 | Cairo | Multiple Hospitals in Cairo | E-test | 470 | 3 | Total | E. coli | 7 |
Ibrahim [46] | 2021 | 2019 | Cairo | Ain Shams University Hospitals | BMD | 100 | 14 | Total | K. pneumoniae, P. aeruginosa, E. coli, Citrobacter | 8 |
Khattab [71] | 2021 | 2020–2021 | Ismailia | Suez Canal University Hospitals | BMD | 116 | 43 | CR | E. coli, K. pneumoniae | 8 |
Mashalya [77] | 2021 | 2016–2019 | Mansoura | Mansoura University Hospitals | BMD | 115 | 7 | Total | E. cloacae, E. aerogenes | 8 |
Negm [45] | 2021 | January 1, 2019– December 31, 2019 | Zagazig | Zagazig University Hospitals | VITEK-2 | 31,638 | 2,141 | Total | K. pneumoniae, E. coli, P. aeruginosa, A. baumannii | 7 |
Ajlan [44] | 2022 | Nov 2020– Mar 2022 | Menoufia | Menoufia University Hospitals | BMD | 155 | 43 | CR | E. coli, K. pneumoniae, P. aeruginosa, A. baumannii, Enterobacter spp., Citrobacter spp. | 8 |
Badran [42] | 2022 | 2021 | Zagazig | Zagazig University Hospitals | CBDE | 90 | 20 | CR | K. pneumoniae, E. coli, P. mirabilis | 6 |
Defrawy [41] | 2022 | 2016–2017 | Giza | Theodor Bilharz Research Institute | VITEK-2 | 50 | 0 | CR | K. pneumoniae, E. coli, E. cloacae, S. marcescens, C. freundii | 6 |
El-Din [40] | 2022 | 2020–2022 | Sohag | Sohag University Hospitals | E-test | 75 | 18 | Total | P. aeruginosa | 6 |
Gaballah [39] | 2022 | 2018–2019 | Alexandria & El Behira | El Shatby University Hospital, Mabart Al Asafra Hospital, Damanhur General Hospital | VITEK-2 | 336 | 18 | Total | K. pneumoniae, E. coli, A. baumannii, P. aeruginosa, S. maltophilia | 7 |
El-Mahallawy [65] | 2022 | 2019 | Cairo | National Cancer Institute | BMD | 196 | 39 | MDR | K. pneumoniae, E. coli, E. cloacae | 8 |
Mohamed [36] | 2022 | Not specified | Cairo | Ain Shams University Hospitals | VITEK-2 | 25 | 3 | Total | P. aeruginosa | 5 |
Mostafa [43] | 2022 | 2018–2019 | Cairo | Abbassia Fever Hospital | E-test | 200 | 9 | Total | E. coli, K. pneumoniae, A. baumannii, P. aeruginosa, Salmonella spp. | 7 |
Ramadan [35] | 2022 | Jan 2020 - Nov 2021 | Zagazig | Zagazig University Hospitals | CBDE | 73 | 8 | Total | K. pneumoniae | 6 |
Shrief [34] | 2022 | Sep 2021– Mar 2022 | Mansoura | Mansoura University Hospitals | BMD | 92 | 30 | CR | E. coli, K. pneumoniae | 7 |
Sorour [33] | 2022 | April– November 2019 | Cairo | Cairo University Hospitals | BMD | 115 | 12 | Total | E. coli, K. pneumoniae, P. aeruginosa, A. baumannii | 8 |
Abdelbary [31] | 2023 | Sep 2022– Feb 2023 | Assiut | Assiut University Children’s Hospital | BMD | 56 | 15 | Total | K. pneumoniae | 7 |
Abozahra [30] | 2023 | Jan– Jul 2022 | Beheira | Damanhour Medical National Institute | BMD | 82 | 32 | Total | K. pneumoniae | 7 |
Elshamy [29] | 2023 | 2020–2021 | Cairo | Kasr Al-Ainy & El-Demerdash Tertiary Care Hospitals | BMD | 19 | 1 | CR | E. coli, K. pneumoniae, P. aeruginosa, A. baumannii | 7 |
Khatib [28] | 2023 | 2020–2022 | Cairo | Multiple Hospitals | BMD | 270 | 11 | Total | K. pneumoniae, P. aeruginosa | 8 |
Mahmoud [27] | 2023 | 2021–2022 | Cairo | Ain Shams University ICU | BMD | 84 | 36 | MDR | K. pneumoniae, E. coli | 7 |
Mohamed [37] | 2023 | 2017–2020 | Alexandria | ICU in a tertiary care hospital | VITEK-2 | 443 | 5 | Total | K. pneumoniae, E. coli, P. aeruginosa, A. baumannii | 7 |
Abdel-Aty [26] | 2024 | Aug 2022– Feb 2023 | Cairo | Kasr Al-Ainy University Hospitals | BMD | 250 | 57 | Total | E. coli, K. pneumoniae, P. aeruginosa, A. baumannii | 8 |
Afify [25] | 2024 | Aug 2020– Apr 2021 | Alexandria | Mabaret El Asafra Laboratories | BMD | 111 | 11 | Total | K. pneumoniae, P. aeruginosa, A. baumannii | 8 |
Ali [24] | 2024 | Mar 2019– Feb 2022 | Zagazig | Zagazig University Hospitals | VITEK-2 | 57 | 8 | CR | K. pneumoniae | 6 |
Alshaikh [23] | 2024 | 2021–2022 | Tanta | Tanta University Hospital | BMD | 100 | 0 | Total | E. coli | 8 |
Edward [22] | 2024 | 2017–2018 | Alexandria | Alexandria Main University Hospital | BMD | 104 | 6 | Total | P. aeruginosa | 8 |
El-Kholy [74] | 2024 | 2021 | Alexandria | Mabaret El Asafra Laboratories | BMD | 94 | 27 | CR | K. pneumoniae | 7 |
Makled [73] | 2024 | 2021–2023 | Menoufia | Menoufia University Hospitals | AD | 80 | 10 | Total | P. aeruginosa, A. baumannii | 6 |
Mohamed [38] | 2024 | 2022 | Zagazig | Zagazig University Hospitals | VITEK-2 | 26 | 3 | CR | K. pneumoniae | 6 |
Elnahriry [21] | 2016 | 2015 | Cairo | Hospital (ICU patient) | BMD | 241 | 1 | Total | E. coli, K. pneumoniae, P. aeruginosa, A. baumannii | 8 |
Attalla, [70] | 2023 | July - December 2020 | Alexandria | Private hospital laboratory with 8 satellite branches covering Alexandria | BMD | NA | 17 | NA | K. pneumoniae | 8 |
Osama [20] | 2019 | 2016 − 2017 | Cairo | Two teaching hospitals and two private clinical labs | DD | 30 | 5 | CR | E. coli, K. pneumoniae, P. aeruginosa, | 6 |
Al-Agamy [69] | 2014 | Jan - Mar 2012 | Cairo | Kasr El Aini Hospital, Dar Al Fouad Hospital | AD | 40 | 2 | CR | A. baumannii | 6 |